In Body’s Shield Against Cancer, a Culprit in Aging May Lurk

The researchers showed that mice purged of senescent cells could run much longer on a treadmill, had larger fat deposits — fat disappears from the skin as people age, causing wrinkles — and developed cataracts much later. Much the same effect was seen in a second experiment, in which dosing did not start until the mice were middle-aged, except that cataracts that had already formed could not be reversed.